免疫化学/甲基化赖氨酸抗体，生物素/100μg/ICP0503
商品编号：
ICP0503
品牌：
immunechem
市场价：
¥7500.00
美元价：
3750.00
产品分类：
细菌抗原
公司分类：
Bacterial_antigen
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Methylated Lysine Antibody, Biotin
|
Product Description | The affinity purified rabbit polyclonal anti-methylated lysine antibody is developed using a technique unique to ImmuneChem. The methylated lysine antibodies are affinity purified using N-methyl (epsilon amino group) lysine on agarose as the affinity matrix. The purified antibody was conjugated to d-biotin via acetylation. Direct labelling of the primary antibody will avoid the use of secondary antibodies therefore eliminating the interference of the secondary antibody conjugates. |
Species | Rabbit |
Formulation | 250 µg/mL in PBS, 50% glycerol |
Immunogen | Methylated KLH conjugates |
Purification | Affinity purified with methyl-lysine and di-methyl-lysine on agarose |
Conjugation | Acetylation with NHS-biotin; Biotin/Ab molar ratio - 10:1 |
Specificity | The antibody recognizes anti-MeK (biotin conjugate) and recognizes proteins methylated on their lysine residues (mono and di-methyl lysine). It does not cross react with acetylated proteins. |
Applications | ELISA (0.25 - 1.0 µg/mL); WB (0.25 - 1.0 µg/mL) |
Scientific Description | MeK is a conserved post-translational modification which is an important biochemical process for many protein-protein interactions. It is found in many proteins, for example calmodulin, cytochrome B, chromosomal proteins, non-histones as well as neural storage body proteins. It has been suggested that methylation of lysine plays an important role in gene silencing. [1-3] |
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. |
Product Specific References | 1.J. Biol. Chem. 2003.278:18346-18352.doi.10.1074/jbc.M300890200 2.J. Biol. Chem. 2002.277:34655-34657.doi:10.1074/jbc.C200433200 3.J. Biol. Chem.2002.277:11621-11624.doi:10.1074/jbc.C200045200 |
品牌介绍
加拿大免疫化学药剂有限公司(ImmuneChem Pharmaceuticals Inc. 简称ICP) 是由加拿大政府资助而创立的生物高科技开发公司。始创立于1997年，公司的研究与开发部门位于加拿大不列颠斯哥伦比亚省大温哥华地区。ICP是一个以蛋白质化学技术和免疫技术为基础的免疫化学药物高科技公司。以固相表面化学技术为基础，以蛋白质分离提纯基础为核心，以免疫技术为应用，致力于开发科研和诊断用免疫球蛋白以及医疗用被动免疫球蛋白，其所创建的ImmuneChem品牌抗体试剂多年来畅销世界各地。
联络我们
