免疫化学/二甲基精氨酸抗体/100μg/ICP0810
商品编号：
ICP0810
品牌：
immunechem
市场价：
¥6500.00
美元价：
3250.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Dimethyl Arginine Antibody
|
Product Description | This antibody was raised from rabbits that were immunized with NG,NG-dimethyl arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG-dimethyl arginine antigen. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (asymmetric dimethylation) residues. |  Western blot of human MMRU cells with ICP0810 (A,B) plus competitive inhibition with free dimethyl arginine (C,D)  Antigen Structure ![[Exposure: 10 Milliseconds]](images/ImmunoChem/140619175329350589.png) IF Staining of MMRU cells | |
Species | Rabbit | ||
Formulation | 250μg/mL antibody stored in PBS, 50% glycerol | ||
Immunogen | NG,NG-dimethyl arginine-KLH conjugates | ||
Purification | Antigen-specific immunoaffinity purification with NG,NG-dimethyl arginine and adsorbed with NG-monomethyl arginine | ||
Specificity | The antibody recognizes proteins with dimethylated arginine residues. It does not cross-react with acetylated proteins or monomethylated proteins. | ||
Species Tested | Human, mouse and pig | ||
Applications | ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL); IHC (5 µg/mL) | ||
Scientific Description | Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. | ||
Product Specific References | 1.J. Proteome Res. 2013. 12 (9): 3884-3899.doi:10.1021/pr400556c2.Proteomics. 2016.16(3): 465-476.doi: 10.1002/pmic.2014005643. Proteomics.2013.13(7): 1059-1064.doi: 10.1002/pmic.2012004774.Proteomics. 2015.15(18): 3209-3218.doi: 10.1002/pmic.2015000755.J. Neurosci. 2015.35(37): 12890-12902.doi: 10.1523/JNEUROSCI.0246-15.20156.The FEBS Journal.https://doi.org/10.1111/febs.15057 |
品牌介绍
加拿大免疫化学药剂有限公司(ImmuneChem Pharmaceuticals Inc. 简称ICP) 是由加拿大政府资助而创立的生物高科技开发公司。始创立于1997年，公司的研究与开发部门位于加拿大不列颠斯哥伦比亚省大温哥华地区。ICP是一个以蛋白质化学技术和免疫技术为基础的免疫化学药物高科技公司。以固相表面化学技术为基础，以蛋白质分离提纯基础为核心，以免疫技术为应用，致力于开发科研和诊断用免疫球蛋白以及医疗用被动免疫球蛋白，其所创建的ImmuneChem品牌抗体试剂多年来畅销世界各地。
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