免疫化学/乙酰赖氨酸抗体，小鼠单克隆/100ug/ICP0390
商品编号：
ICP0390
品牌：
immunechem
市场价：
¥7000.00
美元价：
3500.00
产品分类：
人体抗原
公司分类：
human_antigen
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Acetyl Lysine Antibody, Mouse Monoclonal
|
Product Description | The pan-specific anti-acetyl lysine monoclonal antibody is developed using hybridoma technology and is affinity purified with acetyl-lysine agarose. It recognizes both free acetyl-lysine and acetyl-lysine residues in proteins or peptides. |  Chicken erythrocyte histones were separated by triton-acetic acid-ureapolyacrylamide gel electrophoresis. (1) non-treated and (2) Sodium butyrate (5 mM) treated. Each lane contained 20 ug of total protein. PVDF membrane was probed with mouse monoclonal antibody (ICP0390), which was further detected with goat anti-mouse HRP secondary antibody. | |
Species | Mouse | ||
Isotype | IgGa2 | ||
Formulation | 250 μg/mL in PBS (pH7) with 50% glycerol | ||
Immunogen | Acetylated KLH conjugates | ||
Purification | Affinity chromatography with acetyl-lysine agarose | ||
Specificity | The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA and acetylated MBP. No cross-reaction to non-acetylated proteins. | ||
Applications | ELISA; WB (0.1-0.5 µg/mL); IF (1-5 µg/mL); IP(approximately 10µg/mg crude protein) | ||
Scientific Description | DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylating lysine residues within the proteins. It has been suggested that acetylation of non-histone proteins (e.g., transcription factors) and histones may be involved. Acetylation of these proteins may result in signal transduction within the chromatic domains. | ||
Storage & Stability | Product is stable for 30 days at room temperature. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. | ||
 Immunofluorescent staining of mouse tissue with ICP0390. |
品牌介绍
加拿大免疫化学药剂有限公司(ImmuneChem Pharmaceuticals Inc. 简称ICP) 是由加拿大政府资助而创立的生物高科技开发公司。始创立于1997年，公司的研究与开发部门位于加拿大不列颠斯哥伦比亚省大温哥华地区。ICP是一个以蛋白质化学技术和免疫技术为基础的免疫化学药物高科技公司。以固相表面化学技术为基础，以蛋白质分离提纯基础为核心，以免疫技术为应用，致力于开发科研和诊断用免疫球蛋白以及医疗用被动免疫球蛋白，其所创建的ImmuneChem品牌抗体试剂多年来畅销世界各地。
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