免疫化学/乙酰赖氨酸抗体，FITC/100µg/ICP0385
商品编号：
ICP0385
品牌：
immunechem
市场价：
¥7500.00
美元价：
3750.00
产品分类：
其它天然蛋白
公司分类：
Other_natural_proteins
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Acetyl Lysine Antibody, FITC
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Product Description | The rabbit anti-acetyl lysine antibody is developed using acetylated KLH as the immunogen. It is affinity purified with acetyl lysine agarose, followed by conjugation with fluorescein isothiocyanate. |  Immunoflourescent staining of TSA-treated and non-treated melanoma cells. | |
Species | Rabbit | ||
Formulation | 250 µg/mL in PBS (pH 7) with 50% glycerol | ||
Immunogen | Acetylated KLH conjugates | ||
Purification | Affinity chromatography with acetyl-lysine agarose | ||
Conjugation | FITC:antibody = 10:1 | ||
Applications | For direct immunofluorescence experiments | ||
Scientific Description | Acetylation of lysine is an important, reversible modification. The activities of some proteins are controlled by acetylation of lysine. Histone acetyltransferases (HATs) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) that contain lysine residues. Histone deacetylases (HDACs) remove the acetyl group from the same residue. [1] Acetylation/deacetylation of histones results in cell signalling processes that include gene activity, cell growth, differentiation and apoptosis. [2] In cancer and polyglutamine diseases, the regulation of protein acetylation/deacetylation is impaired (7). Numerous anti-cancer drugs target HDACs. [3] | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is six months from date of shipping if stored properly. | ||
Product Specific References |
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品牌介绍
加拿大免疫化学药剂有限公司(ImmuneChem Pharmaceuticals Inc. 简称ICP) 是由加拿大政府资助而创立的生物高科技开发公司。始创立于1997年，公司的研究与开发部门位于加拿大不列颠斯哥伦比亚省大温哥华地区。ICP是一个以蛋白质化学技术和免疫技术为基础的免疫化学药物高科技公司。以固相表面化学技术为基础，以蛋白质分离提纯基础为核心，以免疫技术为应用，致力于开发科研和诊断用免疫球蛋白以及医疗用被动免疫球蛋白，其所创建的ImmuneChem品牌抗体试剂多年来畅销世界各地。
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