4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:原厂直采,平行进口,授权代理(蚂蚁淘为您服务)
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Crosslinkers > ImmunoChem/Acetyl Lysine Antibody, Biotin/100 µg/ICP0383
商品详细ImmunoChem/Acetyl Lysine Antibody, Biotin/100 µg/ICP0383
ImmunoChem/Acetyl Lysine Antibody, Biotin/100 µg/ICP0383
ImmunoChem/Acetyl Lysine Antibody, Biotin/100 µg/ICP0383
商品编号: ICP0383
品牌: immunechem
市场价: ¥7500.00
美元价: 3750.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白交联剂
公司分类: Crosslinkers
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Acetyl Lysine Antibody, Biotin

Catalog # Pack Size Price(USD)
ICP0383 100 µg $375.00

Quantity:

Product Description
The affinity purified polyclonalrabbitanti-acetylated lysine antibody is developed using acetylated KLH as the immunogen. The acetylated lysine-specific antibody is conjugated with d-Biotin via amine acylation.
Western blot analysis of acetylated proteins from TSA treated (A) and non-treated (B) human melanoma cell (MMRU) lysates.
Species
Rabbit
Formulation
250 µg/mL antibody in PBS, pH 7, with 50% glycerol.
Immunogen
Acetylated KLH conjugate.
Purification
Affinity chromatography with acetyl-lysine agarose.
Conjugation
Acylation with NHS-biotin; biotin:Ab molar ratio = 10:1
Specificity
The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA, and acetylated MBP. No cross-reaction to non-acetylated proteins.
Scientific Description
DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylating the lysine residues within the proteins. It has been suggested that acetylation of non-histone proteins (e.g. transcription factors) and histones may be involved. Acetylation of the proteins may result in signal transduction within the chromatic domains.
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.
Product Specific References
  1. 1.FEBS Lett. 2002.513(1): 124-128.doi:10.1016/S0014-5793(01)03309-9.

品牌介绍
加拿大免疫化学药剂有限公司(ImmuneChem Pharmaceuticals Inc. 简称ICP) 是由加拿大政府资助而创立的生物高科技开发公司。始创立于1997年,公司的研究与开发部门位于加拿大不列颠斯哥伦比亚省大温哥华地区。ICP是一个以蛋白质化学技术和免疫技术为基础的免疫化学药物高科技公司。以固相表面化学技术为基础,以蛋白质分离提纯基础为核心,以免疫技术为应用,致力于开发科研和诊断用免疫球蛋白以及医疗用被动免疫球蛋白,其所创建的ImmuneChem品牌抗体试剂多年来畅销世界各地。